YAZ DRUG INFO
IMPORTANT NOTE: The
following information is intended to supplement, not substitute
for, the expertise and judgment of your physician, pharmacist or
other healthcare professional. It should not be construed to indicate
that use of the drug is safe, appropriate, or effective for you.
Consult your healthcare professional before using this drug.
Drospirenone/Estradiol Tablets (droe-SPYE-re-none/ES-tra-DYE-ol)
COMMON BRAND NAME(S):Angeliq
WARNING: Smoking cigarettes while
using this medication increases your chance of having heart problems.
Do not smoke while using this medication. The risk of heart problems
increases with age (women greater than 35 years of age) and with
frequent smoking (15 cigarettes per day or greater).
USES:Treating certain moderate to severe symptoms of
menopause (eg, hot flashes; dryness, itching, and burning in or
around the vagina). It may also be used for other conditions as determined
by your doctor. YAZ is a combination of progestin and estrogen hormones.
It works by replacing natural progestin and estrogen in women who can no longer
produce enough of these hormone
HOW TO USE: Use YAZ as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with YAZ . Talk to your pharmacist if you have questions about this information.
Take YAZ by mouth with or without food.
Take YAZ on a regular schedule to get the most benefit from it.
Taking YAZ at the same time each day will help you remember to take it.
Continue to take YAZ even if you feel well. Do not miss any doses.
If you miss a dose of YAZ , take it as soon as possible. If it is almost time for your next dose,
skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
SIDE EFFECTS:All medicines may cause side effects, but many people have no,
or minor, side effects. Check with your doctor if any of these most COMMON side effects
persist or become bothersome: Back pain; breast tenderness, pain, or enlargement; headache;
mild hair loss; nausea; nervousness; stomach cramps, bloating, or pain; vaginal spotting or
breakthrough bleeding; vomiting; weight changes.
PRECAUTIONS:YAZ may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines.
Use YAZ with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
YAZ may increase the risk of stroke, heart attack, blood clots, high blood pressure, or similar problems.
The risk may be greater if you smoke.Tell your doctor or dentist that you take YAZ before you receive any medical
or dental care, emergency care, or surgery. YAZ should be discontinued at least 4 to 6 weeks before surgery or at
any time you will be confined to a bed or chair for a long period of time (eg, a long plane flight). Talk to your
doctor about the safe use of YAZ if any of these conditions apply to you. You should perform monthly self-breast
exams and receive yearly breast exams from your doctor while you are taking YAZ . Talk with your doctor if
you are unsure how to properly perform a self-breast exam. Report any lumps to your doctor right away.
DRUG INTERACTIONS: Some MEDICINES MAY INTERACT with YAZ . Tell your health care provider
if you are taking any other medicines, especially any of the following: # Troleandomycin because the risk of
jaundice (yellowing of the skin of eyes) and liver problems may be increased. Angiotensin-converting enzyme (ACE)
inhibitors (eg, lisinopril), angiotensin receptor blockers (eg, valsartan), heparin, nonsteroidal anti-inflammatory
drugs (NSAIDs) (eg, ibuprofen), potassium sparing diuretics (eg, triamterene), or potassium supplements because
the risk of high potassium levels in the blood may be increased. Azole antifungals (eg, ketoconazole),
HIV protease inhibitors (eg, ritonavir), or macrolide antibiotics (eg, erythromycin) because they may increase the
risk of YAZ 's side effects. Barbiturates (eg, phenobarbital), carbamazepine, griseofulvin, hydantoins (eg, phenytoin),
penicillins (eg, amoxicillin), rifampin, St. John's wort, or tetracyclines (eg, doxycycline) because they may
decrease YAZ 's effectiveness. Corticosteroids (eg, prednisone) because the risk of their side effects may be increased by YAZ.
Lamotrigine or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by YAZ.
OVERDOSE: Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center,
or emergency room immediately. Symptoms may include severe or persistent nausea; severe or unusual vaginal bleeding.
NOTES: YAZ is to be used only by the patient for whom it is prescribed. Do not share it with other people.
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Yaz prevents ovulation (the release of an egg from an ovary) and also cause changes in your cervical and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.